Kevin lee:13585952669
Mixer affiliates
Shanghai Hanhong chemical technology co., LTD. Is one of the core
members, said han hong enterprise, founded in 2003, the company's
business includes research and development, reagents and custom
synthesis business. The company has a group of senior research
and development and production management personnel; The research
and development center in college construction, construction of
the pilot plant in jiangsu, reactor reached more than 200 sets of
reaction volume range from 10-5000 - l l.
Binhai said Hanhong biochemical co., LTD is one of the core
members, said han hong enterprise was established in 2005, the
production of fine and specialty chemicals, leading edge products
for unnatural amino acids, protected amino acids, chiral
intermediates and heterocyclic block production. It is located in
jiangsu yancheng coastal chemical industry park (one of China's
famous chemical industrial park). Company covers an area of 35000
square meters, there are four 82 - meter multi-function synthesis
workshop, a pilot plant, a sewage pretreatment workshop and
laboratory. Company at present, 80 employees, has more than 40
sets of reactor, volume 50 l to 8000 l, HPLC, GC, HPCE etc.
Various analytical instruments.
Other associated company, the company in shandong, shanxi,
shijiazhuang has the technology investment and four joint
production enterprises, mainly engaged in chiral reagents,
pharmaceutical intermediates, nucleoside products production.
Relying on the company's research and development strength and
production unit, said han hong enterprises can according to
customer requirements, customized production of fine chemical
products from grams to tons of fine chemical products.
Polypeptide custom synthesis
Hanhong chemical with solid-phase synthesis and core technology,
liquid phase synthesis of the peptides and with the advantages of
its own protection amino acids, so can give customers to provide
quality and cheap custom peptide synthesis business, is China's
main custom peptide synthesis.
The custom synthesis of DNA, RNA
Hanhong chemical in their production nucleoside, on the basis of
the phosphoryl according to monomer, combined with our ability to
solid phase synthesis, can provide customers with different size
of DNA, RNA, custom synthesis business. Low prices, quality and
fast is our goal.
The custom synthesis of organic compounds
Our company owns more than 60 staff in organic synthesis, 15 of
organic synthesis laboratory, there are two multi-function
workshop, can provide customers both at home and abroad from
grams to kilograms to tonnage custom synthesis product. Custom
synthesis is one of our main business direction.
Company profile/Companyintroduction
Our company's business includes three blocks: research and
development with chemicals, fine and specialty chemicals, custom
synthesis. He hong's core competence is a senior ORGANIC
synthesis block (ADVANCED ORGANIC BUILDING BLOCKS) production.
Hanhong has the advantage of amino acids, peptides, nucleotide,
production technology, said han hong through technical
investment, joint production holding companies all over the
country set up have four, six joint production enterprises, and
establish the enterprise one. Company engaged in class from grams
to kilograms, the tonnage of senior ORGANIC synthesis block
(ADVANCED ORGANIC BUILDING BLOCKS) production, advantage product
is a natural amino acid (4 production lines, 200 tons/year),
protected amino acids (three production lines, 50 tons/year),
peptides (article 2000 peptide/month), nucleoside and nucleotide
(3 production lines, 80 tons/year), chiral separation agents (2
production lines, 300 tons/year) and some of the heterocyclic
intermediates (2 production lines, 150 tons/year).
News
The company patent authorized acylation of immobilized enzyme
technology. Application (patent no. : 200910047876.0
In this paper,
The invention discloses a kind of preparation methods of
immobilized amine acylation enzyme, it contains the following
steps: in the water, 60-90 ℃ dissolve immobilized material
(carrageenan and gelatin), cooled to 40-60 ℃, add amide acylation
enzyme, mixed evenly, and then the mixture flow to the
temperature of 20-35 ℃ in the organic solvent, stirring, particle
filter, adding the particles to KCl in aqueous solution, curing,
can produce amino acylation enzyme immobilization, among them,
described the KCl contains glutaraldehyde in aqueous solution.
The present invention also made public by its amino acylation of
immobilized enzyme and its application. The preparation method of
the invention can effectively reduce the freezing point of
immobilized materials, and
Amino acylation of immobilized enzyme is granule, good
flowability, can effective convenient split optical activity of
amino acids.
Companies to adopt new technology production FMOC TRP (BOC) - OH
series products
Advanced foam extinguishing system put into use
Mr Ma Shizhong company won the first prize in Shanghai science
and technology progress
Enzymatic production of natural amino acid project won the first
prize of Shanghai science and technology progress
Simmons - Smith reaction
My company's booth no. : 2014 CPHI Shanghai W3B89. Show time:
June 26-28, 2014
The 70th B3R09 API exhibition booths, and on April 25, 2013-27,
wuhan international exhibition center
My company's booth no. : 2013 CPHI Shanghai E5D06. Show time:
June 25 to 27, 2013
Company of preparation methods of immobilized amine acylation
enzyme patent authorized
Company profile
Hanhong reagent
Fine and specialty chemicals
The custom synthesis
Companies use penicillin acylation enzyme on large-scale split
BETA - amino acids
Company of enzyme catalysis process new reactor to obtain the
national patent
The advantage of Hanhong:Hanhong high-end chemical reagent is
introduced.
Hanhong in unnatural amino acids, protected amino acids,
peptides, nucleotides, chiral reagents .such as development and
production has nearly 10 years of history, the kinds of
the products reached more than ten thousand, the scale of
production from grams to
kilograms, they constitutes the core foundation of he hong
reagent. In recent years, said
han hong to further expand the size of the reagent production,
resource integration and to
strengthen the domestic suppliers, varieties and expand to the
advanced organic building
blocks and organic short reagent, can supply varieties reached
more than 20000.
Staff: at present, said han hong has nine reagent synthesis lab
specializes in BULDING
BLOCKS production (laboratory four unnatural amino acids and
protect amino acids,
polypeptide laboratory 1, chiral reagent laboratory 1, BUILDING
three BLOCKS laboratory).
A total of nearly 60 person team of reagent production.
Facilities: laboratory reagent synthesis area of 2000 square
meters, in addition reagent
workshop of 1000 square meters of form a complete set of 50 l -
200 l of small equipment
engaged in the reagent production.
Mode:
Hanhong company laboratory or synthetic reagent workshop -
refining - analysis - packing -
reagent products; External resources integration - purchased
reagents raw material - - refining - analysis - packing - reagent
products; In pieces he hon advantages of high-end chemical
reagent (Hanhong) category. natural amino acid and its
derivatives, protect amino acid series, dipeptide and ripeptide,
chiral separation and chiral reagents in total about 12000
varieties, their
synthesis, for hanhong company basically is hanhong reagents at
the core of the product,
has the absolute cost advantages and technological advantages.
And reagents in organic
synthesis, heterocyclic block, said han hong part of their
production, the other part is
hanhong resources integration, namely, buy from local suppliers,
inspection, refined,
testing and packaging in the form of production.
Hanhong has the advantage of the fine and specialty chemicals.
Hanhong is fine and specialty chemicals producer, is also fine
and specialty chemicals traders and service providers. Hanhong`s
core advantage is a factory, has a professional technical team,
so their production varieties and trade varieties, said han hong
scheme can provide professional technology and service, resolve
customer about product quality and technical requirements, this
is John hong trading company is very different with other place.
When hanhong in the fine and specialty chemicals production has
the core technology advantages:
The synthesis and resolution of the natural amino acid;
(2) to protect the synthesis of amino acids;
(3) short peptide of liquid phase synthetic technologies and
solid-phase synthesis of peptides.
(4) of natural nucleoside synthesis technology;
(5) chiral separation agents and the synthesis of chiral BUILDING
BLOCKS;
6 senior organic block of green synthesis technology;
He hong as a trader, has the following advantage of professional
technology and service plan:
1) hanhong knows product manufacturing process, can give
customers process route, process cost accounting and process
control points data, can according to the characteristics of the
needs of customers to assist manufacturers reasonable adjustment
process according to customer requirements, for the manufacturers
to provide technical services;
(2) hanhong factory owns advanced analysis and test instrument,
is ISO9001 enterprise, the ability to have a good QA and QC team,
so no matter he hong factory products or trade, said han hong can
carry on the rigorous analysis of the quality of product, can
also according to customer requirements for the QA process
control. Can also assist cooperation manufacturers to improve QA
and QC management.
(3) hanhong owns organic synthesis laboratory and organic
synthesis team, so you can accept custom synthesis business. When
a project, first of all done in the laboratory test and pilot
test, process is finished, a situation is directly in the
company's production base, another is in outsourcing production
cooperation company.
(4) hanhong company engaged in the fine and specialty chemicals
has been more than 10 years, be familiar with the domestic
production situation of fine and specialty chemicals industry,
familiar with import and export business, thus can fight for a
more reasonable price to customers and interests.
Polypeptide custom
The rigorous work attitude, high quality source of raw materials,
the synthesis of rich experience, strong production and research
and development, and quality management experience for many
years, adumbrative we will provide customers with the most
excellent synthesis service. Shanghai hanhong chemical technology
co., LTD. As one of the earliest companies involved in peptide
synthesis and the research and development, we start from peptide
raw materials, in the domestic customers to provide more high
quality peptide raw materials at the same time, also in our
peptides to further development. Now, we are offering a peptide
products have been widely used in the world of colleges and
universities, scientific research institutions of experimental
studies. And, we also offer domestic drug manufacturers peptide
API. Company directly engaged in peptide synthesis of front-line
staff increased to 30 people, and a high performance liquid
chromatography (HPLC) purification team composed of more than 20
people.
Company in addition to the synthetic technology, also USES the
automatic peptide synthesis equipment specializing in the
production of mg, more research and development of series of
varieties of peptide products to meet customer needs. We have
developed different solid phase synthesis method to meet the
demand of commercial level polypeptide.
Products and services:
Normal linear peptide: chain length to 140 amino acids, mg to
grams, purity can reach 99%;
Simple modification peptide: free N acetylation, end amidation;
Complex modifying peptides: fat peptide, peptide phosphate (Ser,
Thr, Tyr), cyclic peptide (amide, disulfide bond), fluorescent
marker peptides (FAM, FITC), BIOTIN labeling peptides (BIOTIN),
compound antigen peptide (MAP), etc.;
Protein crosslinking: KLH, BSA and OVA;
Contain special amino acid peptide: D amino acid and various
kinds of amino acid derivatives;
Scope: different purity coarse peptide, > 70% and > 80% and > 90%
and > 95% and > 98% and > 99%;
Amino acids
Chinese pharmacopoeia 2005 edition contains varieties: propylene
ammonia gonadorelin acetate
Chinese pharmacopoeia 2005 edition contains varieties: valine
Chinese pharmacopoeia 2005 edition contains varieties: acetic
acid lysine
Chinese pharmacopoeia 2005 edition contains varieties: arginine
The Chinese pharmacopoeia 2005 edition contains varieties:
tyrosine
Chinese pharmacopoeia 2005 edition contains varieties: proline
The Chinese pharmacopoeia 2005 edition contains varieties:
cystine
Chinese pharmacopoeia 2005 edition contains varieties: arginine
hydrochloride
Chinese pharmacopoeia 2005 edition contains varieties: lysine
hydrochloride
Chinese pharmacopoeia 2005 edition contains varieties: histidine
hydrochloride
Chinese pharmacopoeia 2005 edition contains varieties: cysteine
hydrochloride
The Chinese pharmacopoeia 2005 edition contains varieties:
leucine
The Chinese pharmacopoeia 2005 edition contains varieties:
histidine
Chinese pharmacopoeia 2005 edition contains varieties: monosodium
glutamate
The Chinese pharmacopoeia 2005 edition contains varieties:
glutamic acid
