Targeted News Service (subscription) The abstract of the patent published by the U.S. Patent and Trademark Office states: "Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian ... and more »
pharmabiz.com Iniparib (BSI-201; SAR240550) is a benzamide (4-iodo-3-nitrobenzamide) that is structurally related to nicotinamide. Iniparib was initially designed as a poly (ADP-ribose) polymerase (PARP) 1 inhibitor based on the benzamide structure. Recent research ...
Edubourse.com (Communiqué de presse) L'iniparib a été conçu au départ comme un inhibiteur de la poly (ADPribose) polymérase (PARP) de type 1, en raison de sa structure benzamide . De récentes recherches ont néanmoins montré que l'iniparib ne peut pas inhiber la PARP1 à des concentrations ...
Zonebourse.com L'iniparib (BSI-201 ; SAR240550) est une benzamide (4-iodo-3-nitrobenzamide) structurellement proche de la nicotinamide. L'iniparib a été conçu au départ comme un inhibiteur de la poly (ADP- ribose) polymérase (PARP) de type 1, en raison de sa ... and more »
4-traders (press release) Patients were randomized to receive a standard chemotherapy regimen of carboplatin AUC 5 on Day 1 and gemcitabine 1000 mg/m2 on Day 1 and 8 of each 21-day cycle, with or without iniparib 5.6 mg/kg on Day 1, 4, 8 and 11. Patients in the study received ... and more »
