7thSpace Interactive (press release) Conclusions: Based on these data and previous transgenic TDP-43 studies in animals or cell cultures, we suggest that one major common consequence of the different ALS-associated TDP-43 mutations is the stabilization of the hTDP-43 polypeptide .
Mississippi Business Journal (blog) In the second pre-revenue category, first place was awarded to Thermally Targeted Therapeutics, of Ridgeland, which works to eliminate side effects of therapeutic approaches for cancer by using a thermally responsive polypeptide . Second place was ...
Zee News In the study, researchers conducted a biochemical analysis of the structure to learn how ATP binding allosterically opens the polypeptide -binding site. In order for Hsp70 to do its job of regulating its binding to unfolded polypeptide substrates, it ...
News-Medical.net The team found that when Hsp70 binds ATP it promotes the allosteric opening of the polypeptide binding site. "Due to their essential roles in protein trafficking and proper folding since mis-folded proteins can disrupt cell function, Hsp70s are ...
