Techsonian (press release) The company's lead product candidate is vosaroxin, an anti-cancer quinolone derivative for the treatment of acute myeloid leukemia or AML. It has accomplished a Phase III, randomized, double-blind, placebo-controlled, and pivotal clinical trial of ...
PR.com (press release) Bioo Scientific now offers the broadest range of commercial kits for quinolone residue detection, with the launch of several new ELISAs. The AuroFlow™ Fluoroquinolone Strip Test Kit for Meat, the AuroFlow™ Fluoroquinolone Strip Test Kit for Milk and ...
The Oncology Report Vosaroxin is an investigational, first-in-class anticancer quinolone derivative that was granted fast track designation by the Food and Drug Administration in 2011 for the potential treatment of relapsed or refractory acute myeloid leukemia (AML) in ... and more »
Medscape Final analysis showed that patients treated with the quinolone derivative vosaroxin (Qinprezo, Sunesis) plus the chemotherapy cytarabine had better overall su...
MedPage Today Vosaroxin, he said, is a derivative of the quinolone antibiotics that has several attractive characteristics: it is independent of p53, it is not a substrate of the P-gp glycoprotein, and it does not form reactive oxygen species. It is also minimally ... and more »
GlobeNewswire (press release) In vitro models have shown activity of the EV-035 series of molecules in gram-negative and gram-positive bacteria, including multi-drug res...
Healio Vosaroxin (Quinprezo, Sunesis) is a first-in-class anticancer quinolone derivative active in AML. “Vosaroxin is minimally metabolized, evades P glycoprotein receptor–mediated efflux and has activity independent of p53 status,” Farhad Ravandi, MD ...
Monthly Prescribing Reference Quinolones and fluoroquinolones are effective broad-spectrum antibiotics that are used to treat numerous infections; however, concerns about possible teratogenic effects seen in animal studies have limited their use during pregnancy. In a study ...
Renal and Urology News Dr. Shoshany's team reported that quinolone resistance was high in both gram negative and gram positive bacteria. “One of the important measures to reduce the risk of postoperative infection is the preoperative antibiotic treatment to sterilize the ...
Packet Online Ltd. The application says the company is "the leading manufacturer and supplier of fat-soluble vitamins, quasi-vitamins, quinolone antibiotics, anti-drug resistant antibiotics and other products for the global market." ZMC says it is the second-largest ...