Gastroenterology & Endoscopy News Cadazolid (CDZ; ACT-179811, Actelion) is a new quinolonyl-oxazolidinone with structural elements of the oxazolidinone as well as the quinolone class. It is a strong inhibitor of C. difficile protein synthesis that leads to the suppression of toxin and ...
GlobeNewswire (press release) QINPREZO™ (vosaroxin) is an anti-cancer quinolone derivative (AQD), a class of compounds that has not been used previously for the treatm...
Cancer Network A phase III trial of vosaroxin, a quinolone derivative of a class not previously used in cancer therapy, failed to meet its primary endpoint in patients with first relapsed or refractory acute myeloid leukemia (AML). The study did show promise with ...
Medscape Methods: A case-control study was carried out among a cohort of subjects who had visited an ophthalmologist in the Province of British Columbia, Canada from 2000 to 2007. Cases were identified as those newly diagnosed with glaucoma (ICD-9 360).