MarketWatch QINPREZO™ (vosaroxin) is an anti-cancer quinolone derivative (AQD), a class of compounds that has not been used previously for the treatment of cancer. Preclinical data demonstrate that QINPREZO both intercalates DNA and inhibits topoisomerase II, ... and more »
TheFishSite.com While only a few antibiotics are approved for aquaculture and exact data on use is hard to come by (see below) at least two critically important antibiotics – tetracyclines and oxolinic acid, a third generation quinolone – are in regular use in Chile ... and more »
Family Practice News Digital Network Key clinical point: Levofloxacin prophylaxis isn't recommended after kidney transplant, because it failed to prevent BK viruria and ...
Gastroenterology & Endoscopy News Cadazolid (CDZ; ACT-179811, Actelion) is a new quinolonyl-oxazolidinone with structural elements of the oxazolidinone as well as the quinolone class. It is a strong inhibitor of C. difficile protein synthesis that leads to the suppression of toxin and ...
GlobeNewswire (press release) QINPREZO™ (vosaroxin) is an anti-cancer quinolone derivative (AQD), a class of compounds that has not been used previously for the treatm...
Cancer Network A phase III trial of vosaroxin, a quinolone derivative of a class not previously used in cancer therapy, failed to meet its primary endpoint in patients with first relapsed or refractory acute myeloid leukemia (AML). The study did show promise with ...
Medscape Methods: A case-control study was carried out among a cohort of subjects who had visited an ophthalmologist in the Province of British Columbia, Canada from 2000 to 2007. Cases were identified as those newly diagnosed with glaucoma (ICD-9 360).
AAP News (subscription) Of concern, however, was that 68% of the isolates were resistant to nalidixic acid (a quinolone antibiotic), which is used in the laboratory to test for resistance. The concern is based on that fact that quinolones are one of the antibiotics commonly ... and more »
Street Newswire (registration) Redhill Biopharma Ltd – ADR (NASDAQ:RDHL) jumped briefly this morning before dipping into the red recently in the U.S. pre-market session on Monday after the U.S. FDA granted a Qualified Infectious Disease Product (QIDP) fast-track designation to its ... and more »
